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Byung-Hyun Park Selected Research

Type 1 Diabetes Mellitus (Autoimmune Diabetes)

4/2015Polyphenols isolated from Broussonetia kazinoki prevent cytokine-induced β-cell damage and the development of type 1 diabetes.
5/2014Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice.
11/2013The efficacy of SPA0355 in protecting β cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes.
1/2011A prenylated flavan from Broussonetia kazinoki prevents cytokine-induced β-cell death through suppression of nuclear factor-κB activity.
1/2011Butein from Rhus verniciflua protects pancreatic β cells against cytokine-induced toxicity mediated by inhibition of nitric oxide formation.
9/2009Dihydroavenanthramide D protects pancreatic beta-cells from cytokine and streptozotocin toxicity.
4/2009Fructus Xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation.
2/2009Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.
10/2008Beneficial effect of Flos magnoliae extract on multiple low dose streptozotocin-induced type 1 diabetes development and cytokine-induced beta-cell damage.
9/2008Making insulin-deficient type 1 diabetic rodents thrive without insulin.
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Byung-Hyun Park Research Topics

Disease

26Neoplasms (Cancer)
03/2024 - 03/2002
26Inflammation (Inflammations)
01/2023 - 11/2008
15Type 1 Diabetes Mellitus (Autoimmune Diabetes)
04/2015 - 05/2003
15Insulinoma
09/2010 - 05/2003
14Obesity
07/2020 - 12/2006
12Necrosis
12/2022 - 08/2011
10Rheumatoid Arthritis
07/2023 - 04/2003
10Insulin Resistance
01/2019 - 12/2013
9Body Weight (Weight, Body)
04/2020 - 07/2006
8Carcinogenesis
01/2022 - 01/2009
7Fibrosis (Cirrhosis)
06/2022 - 09/2004
7Carcinoma (Carcinomatosis)
01/2020 - 12/2007
7Arthritis (Polyarthritis)
12/2018 - 06/2008
6Infections
11/2022 - 01/2002
6Neoplasm Metastasis (Metastasis)
10/2021 - 02/2013
6Breast Neoplasms (Breast Cancer)
01/2021 - 07/2009
6Osteosarcoma (Osteogenic Sarcoma)
11/2020 - 09/2011
6Hyperglycemia
01/2020 - 09/2007
6Experimental Arthritis
03/2016 - 08/2010
5Glucose Intolerance
04/2020 - 05/2014
5Ischemia
01/2017 - 06/2008
4Bone Resorption
03/2024 - 03/2011
4Psoriasis (Pustulosis Palmaris et Plantaris)
07/2023 - 01/2021
4Reperfusion Injury
12/2022 - 06/2008
4Type 2 Diabetes Mellitus (MODY)
01/2020 - 07/2014
4Hypoxia (Hypoxemia)
09/2017 - 04/2003
4Experimental Melanoma
10/2012 - 06/2008
3Non-alcoholic Fatty Liver Disease
01/2023 - 01/2017
3Liver Diseases (Liver Disease)
06/2022 - 01/2020
3Osteoporosis
10/2020 - 01/2016
3Hyperlipidemias (Hyperlipidemia)
06/2015 - 06/2008
3Leukemia
07/2007 - 01/2002
2Autoimmune Diseases (Autoimmune Disease)
07/2023 - 05/2014
2Hepatocellular Carcinoma (Hepatoma)
01/2023 - 12/2007
2Prostatic Neoplasms (Prostate Cancer)
01/2023 - 01/2021
2Cholestasis
06/2022 - 04/2022
2Stomach Neoplasms (Stomach Cancer)
05/2021 - 07/2009
2Dermatitis
01/2021 - 01/2021
2Osteoarthritis
01/2021 - 04/2014
2Bone Diseases (Bone Disease)
10/2020 - 09/2017

Drug/Important Bio-Agent (IBA)

27CytokinesIBA
12/2022 - 05/2003
13Proteins (Proteins, Gene)FDA Link
01/2023 - 12/2013
12Sirtuin 1IBA
07/2023 - 10/2008
12SirtuinsIBA
01/2023 - 07/2013
10Insulin (Novolin)FDA Link
01/2021 - 09/2007
8Glucose (Dextrose)FDA LinkGeneric
01/2021 - 10/2008
8Streptozocin (Streptozotocin)FDA Link
04/2015 - 07/2006
8Interleukin-1beta (Interleukin 1 beta)IBA
09/2010 - 05/2003
7Interferon-gamma (Interferon, gamma)IBA
07/2010 - 05/2003
6CateninsIBA
01/2022 - 01/2013
6LipidsIBA
11/2016 - 09/2004
6LeptinIBA
03/2015 - 09/2004
6NF-kappa B (NF-kB)IBA
02/2011 - 04/2003
5Transaminases (Aminotransferases)IBA
12/2022 - 08/2011
5Indicators and Reagents (Reagents)IBA
10/2021 - 07/2009
5Blood Glucose (Blood Sugar)IBA
07/2020 - 07/2015
5AMP-Activated Protein KinasesIBA
01/2018 - 01/2015
4EnzymesIBA
04/2020 - 06/2008
4SPA0355IBA
01/2019 - 11/2013
4Caspase 3 (Caspase-3)IBA
01/2019 - 01/2002
3p21-Activated KinasesIBA
03/2024 - 01/2022
3Histone Deacetylases (Histone Deacetylase)IBA
07/2023 - 01/2021
3NAD (NADH)IBA
01/2023 - 01/2022
3Therapeutic UsesIBA
06/2022 - 01/2014
3Bile Acids and Salts (Bile Acids)IBA
06/2022 - 01/2020
3Imiquimod (Aldara)FDA LinkGeneric
12/2021 - 01/2021
3Protein Kinases (Protein Kinase)IBA
01/2021 - 10/2015
3Estrogens (Estrogen)FDA Link
10/2020 - 01/2019
3Reactive Oxygen Species (Oxygen Radicals)IBA
05/2019 - 06/2008
3Phosphotransferases (Kinase)IBA
01/2018 - 05/2013
3Metformin (Glucophage)FDA LinkGeneric
08/2016 - 12/2013
3OvalbuminIBA
12/2014 - 09/2010
3Matrix Metalloproteinases (MMPs)IBA
09/2013 - 05/2011
3Complementary DNA (cDNA)IBA
07/2013 - 09/2004
3pregna-4,17-diene-3,16-dione (guggulsterone)IBA
10/2012 - 06/2008
3sulforaphaneIBA
09/2011 - 06/2008
3Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2008 - 01/2002
3PerforinIBA
12/2007 - 01/2002
2salicylhydroxamic acid (SHAM)IBA
12/2022 - 10/2015
2BilirubinIBA
06/2022 - 04/2022
2Interleukin-23 (Interleukin 23)IBA
12/2021 - 01/2021
2Cadherins (E-Cadherin)IBA
05/2021 - 01/2018
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2021 - 01/2021
2Small Interfering RNA (siRNA)IBA
01/2021 - 09/2013
2Sirtuin 2IBA
01/2021 - 01/2017
2olaparibIBA
11/2020 - 05/2018
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2020 - 05/2018
2AntioxidantsIBA
07/2020 - 09/2009
2CholesterolIBA
01/2020 - 06/2015
2CollagenIBA
01/2019 - 12/2018
2Conditioned Culture MediaIBA
01/2019 - 01/2016
2DNA (Deoxyribonucleic Acid)IBA
05/2018 - 01/2009
2InterferonsIBA
01/2018 - 11/2007
2VimentinIBA
01/2018 - 12/2007
2Adenosine Monophosphate (AMP)IBA
01/2018 - 01/2018
2Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
01/2018 - 07/2015

Therapy/Procedure

6Therapeutics
01/2021 - 02/2007
3Ligation
06/2022 - 01/2020
2Oral Administration
06/2022 - 04/2022
2Intradermal Injections
12/2021 - 01/2021